Home | About IJMPO | Editorial board | Search | Ahead of print | Current Issue | Archives | Instructions | Subscribe | Advertise | Contact us |  Login 
Indian Journal of Medical and Paediatric Oncology
Search Article 
  
Advanced search 
 
Year : 1996  |  Volume : 17  |  Issue : 3  |  Page : 141-146

The role of TDF and ERD concepts in concurrent radiotherapy-5 FU chemotherapy treatment for carcinoma of base of tongue.


Dept of Radiation Physics, Kidwai Memorial Institute of Oncology, Bangalore, India

Correspondence Address:
H Vaithianathan
Dept of Radiation Physics, Kidwai Memorial Institute of Oncology, Bangalore, India

Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Fourty four patients with histopathologically proven squamous cell carcinoma of base tongue were treated with concurrent Radiotherapy and Chemotherapy(RT+CT)during 1987-1989. All patients were treated with a combination of Cobalt-60 teletherapy and Chemotherapy with 5-Flurouracil. External radiotherapy(EXRT)dose varied from 40 Gy to 71Gy in 20 to 37 fractions over 28 to 70 days. Treatment results in terms of response rate, status and complication rate were correlated with Dose. Time dose Fractionation factor(TDF)and Extrapolated Response Dose(ERD). There was a sharp increase in mucositis and overall complication rates with increasing dose. The complication rate increased beyond a dose of 50 Gy(p=NS). There was a sharp increase in response rate beyond a dose of 50 Gy(p,0.005). Mucositis and overall complication rates did not correlate with TDF(p=NS). A sharp increase in nodal and overall response rate beyond a TDF of 80(p0.005)was noted. Mucosistis and overall complication rates indicated lack of correlation with ERD(


[PDF Not available]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed446    
    Printed49    
    Emailed0    
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal