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Indian Journal of Medical and Paediatric Oncology
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Year : 1997  |  Volume : 18  |  Issue : 3  |  Page : 80-88

Gestational trophoblastic disease : experience at the government hospital for women/institute of obstetrics & gynaecology


Government Hospital for Women, Chennai

Correspondence Address:
K Kalaichelvi
Government Hospital for Women, Chennai

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Source of Support: None, Conflict of Interest: None


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152 patients with Gestational Trophoblastic Disease (G T D) were treated at Department of Medical Oncology, Government Hospital for Women/Institute of Obstetrics & Gynaecology, Chennai; from August 1988 to June 1996. Of the 152 patients, 71 (46.5 percent) were followed up for Hydatiform Moles (HM), 44 (29 percent), 15 (10 percent) and 22 (14.5 percent) were treated for Persistent Molar Disease (PMD), Invasive mole (IM) and Choriocarcinoma respectively. Forty five (29.6 percent) were 20 years of age, 101 (66.4 percent) were between 21 and 39 years of age and 6 (4 percent) were 40 years of age. Treatment results show 100 percent complete remission (CR) rates in patients with Persistent Molar Disease and Invasive Mole, 50 percent and 75 percent CR rates in metastatic and non-metastatic choriocarcinoma respectively. Chemotherapy was the main form of treatment. Adjuvant hysterectomy and radiotherapy had been used in selected patients. There were 48 pregnancies in patients followed up, resulting in 40 live births and 4 cases of Repeat Moles have been noted.


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