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Indian Journal of Medical and Paediatric Oncology
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Year : 1998  |  Volume : 19  |  Issue : 3  |  Page : 76-82

Strategies of reduce the mortality from childhood Cancer in developing countries


Department of Medical & Paediatric Oncology, Kidwai Memorial Institute of Oncology Bangalore

Correspondence Address:
N Lalitha
Department of Medical & Paediatric Oncology, Kidwai Memorial Institute of Oncology Bangalore

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Source of Support: None, Conflict of Interest: None


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Taking guidelines from the west in reducing mortality from paediatric cancer, strategies that can be adopted in developing countries are, to understand magnitude of problem, to know the incidence and pattern and strategies for early diagnosis, for optimal treatment including and pattern and strategies for early diagnosis, for optimal treatment including supportive care, and to prevent late complications. Preliminary experiences from KIMIO, Bangalore, in this direction are highlighted. Children under 15 years from more than 1/3rd of the population. The average cancer incidence in children under 15 years is 5 percent in boys and 2.5 percent in girls. Lymphoid neoplasias (A.L.L and NHL) is the most common cancer, 35-40 percent in boys and 25-30 percent in girls. Next comes Hodgkin's disease and brain tumours in boys and brain tumours in girls. Improved trends in survival with reference to Hodgkin's disease and A.L.L are given as examples. 25 percent of total Hodgkin's diseases are under 15 years of age and majority present with 'B' symptoms and Ann Arbor Stages III and IV. Before 1981, with only RT none survived beyond 1 year with CT (COPP) and involved field radiotherapy to bulky sites, present 5 years survival has reached more than 85 percent. Majority of A.L.L belong to high risk group and with introduction of protocol based treatment since 1987 (MCP 841 of NCI, USA), 30 months survival is at present more than 60 percent.


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