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Indian Journal of Medical and Paediatric Oncology
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Year : 2003  |  Volume : 24  |  Issue : 3  |  Page : 39

Fournier's gangrene in a patient on aggressive chemotherapy for acute lymphoblastic leukemia : a case report


Dept. of Medical and Paediatric Oncology, Bhagwan Mahavir Cancer Hospital and Research Centre, Jaipur, India

Correspondence Address:
A Bapna
Dept. of Medical and Paediatric Oncology, Bhagwan Mahavir Cancer Hospital and Research Centre, Jaipur, India

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Source of Support: None, Conflict of Interest: None


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Fournier's Gangrene is a form of necrotising fascitis which affects perineum and scrotum and is a fulminating gangrene involving the fascia. Predisposing factors include diabetes mellitus, chronic renal failure, malignancy, poor nutrition with alcohol abuse. Fournier's gangrene is caused by penetration of the gastrointestinal or urethral mucosa by gram-negative bacteria, enterococci or anaerobes such as bacteroides species and peptostreptococci. Clinical features include severe pain, necrotising fascitis which may involve the anterior abdominal wall, gluteal muscle, scrotum and penis. This is the first case described in the setting of acute lymphoblastic leukemia, (ALL) though there are few case reports of Fournier's gangrene in acute non lymphoblastic leukemias (ANLL).


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