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Indian Journal of Medical and Paediatric Oncology
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REVIEW ARTICLE
Year : 2008  |  Volume : 29  |  Issue : 1  |  Page : 27-38

Current strategies in the management of pediatric hodgkin's lymphoma


Department of Pediatric Hematology Oncology, Sir Ganga Ram Hospital, Rajender Nagar, New Delhi-110 060, India

Correspondence Address:
Veronique Dinand
Department of Pediatric Hematology Oncology, Sir Ganga Ram Hospital, Rajender Nagar, New Delhi-110 060
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-5851.51443

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Pediatric Hodgkin's lymphoma is currently one of the most curable childhood malignancies. Therapy is stratified based on disease stage and the presence of adverse prognostic factors. Optimal treatment strategy in pediatric remains controversial, especially in case of advanced disease. Risk-adapted combined modality therapy is the standard of care in favourable and unfavourable early disease. Chemotherapy-alone protocols are advocated by some groups, and show similar outcome, although isolated reports favour additional involved-field radiotherapy. Interim and post-therapy positron emission tomography (PET) is emerging as a tool to avoid radiation or to intensify therapy. Responseadapted therapy is a most effective new approach in order to decrease treatment related long-term toxicity while maintening high cure rates.


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