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Indian Journal of Medical and Paediatric Oncology
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CASE REPORT
Year : 2010  |  Volume : 31  |  Issue : 1  |  Page : 36-38

Florid plasmacytosis in a case of acute myeloid leukemia: A diagnostic dilemma


1 Department of Hematology, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, India
2 Department of Hematology, Kasturba Medical College, Manipal Academy of Higher Education, Mangalore, India

Correspondence Address:
Aruna Rangan
C-277, East End Apartments, Mayur Vihar Phase I Extension, New Delhi - 110 096
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-5851.68853

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The association of acute myeloid leukemia (AML) with plasmacytosis is a known, although rare event. There are very few case reports documenting an increase in the number of plasma cells at the time of AML diagnosis. Here, we present the case of a 65-year-old male diagnosed as acute myelomonocytic leukemia with exuberant plasmacytosis, which posed a difficulty in diagnosis. Paracrine interleukin-6 production by leukemic blast cells is thought to contribute to this associated reactive plasma cell proliferation.


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