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Indian Journal of Medical and Paediatric Oncology
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CASE REPORT
Year : 2011  |  Volume : 32  |  Issue : 2  |  Page : 105-108

Embryonal carcinoma in androgen insensitivity syndrome


1 Department of Gynecologic Oncology, Dr. B. Borooah Cancer Institute, Guwahati, India
2 Department of Pathology, Dr. B. Borooah Cancer Institute, Guwahati, India
3 Department of O&G, Sikkim Manipal Institute of Medical Sciences, Sikkim, India

Correspondence Address:
Debabrata Barmon
Department of Gynecologic Oncology, Dr. B. Borooah Cancer Institute, Guwahati, Assam
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-5851.89794

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Embryonal cell carcinoma is a rare clinical entity. We report a case of a 20-year-old patient who presented with lump lower abdomen for last two months with primary amenorrhea and poorly developed secondary sexual characteristics. Ultrasonography (USG) whole abdomen showed lower abdominal mass approximately 15΄15΄10 cm, probably neoplastic changes in intra-abdominal testis, with mild ascites, no uterus and ovaries. Fine needle aspiration cytology from the tumor mass reported the possibility of non-seminomatous germ cell tumor, possibly embryonal carcinoma. The patient received three cycles of neo-adjuvant chemotherapy (Regime Bleomycin, Etoposide and Cisplatin) followed by laparotomy, at laparotomy (L) orchidectomy with removal of tumor, (R) orchidectomy, omentectomy and appendisectomy was performed. Postoperatively the patient received two more cycles of chemotherapy of the same regime. The patient has been under close follow-up for the last three years with no evidence of disease.


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