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Indian Journal of Medical and Paediatric Oncology
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Year : 2015  |  Volume : 36  |  Issue : 2  |  Page : 79-84

Indian Council of Medical Research consensus document for the management of gall bladder cancer

1 Department of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
2 Mazumdar Shaw Cancer Centre, Narayana Health, Bengaluru, Karnataka, India
3 Department of GI Surgery, SGPGI, Lucknow, Uttar Pradesh, India
4 Department of Medical Oncology, IRCH, All India Institute of Medical Sciences, New Delhi, India
5 Department of Surgical Oncology, Chittaranjan National Cancer Institute, Kolkata, West Bengal, India
6 Department of Surgery, Army Hospital, Rohtak, Haryana, India
7 All India Institute of Medical Sciences, Saket Nagar, Bhopal, Madhya Pradesh, India
8 HIMS, Jolly Grant, Dehradun, Uttarakhand, India
9 Department of GI Surgery, All India Institute of Medical Sciences, New Delhi, India
10 Department of Radiotherapy, RIMS, Imphal, Manipur, India
11 Indian Council of Medical Research, New Delhi, India
12 Department of Radiation Oncology, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
Hari Shankar Shukla
Department of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0971-5851.158829

Rights and Permissions

  • The document is based on consensus among the experts and best available evidence pertaining to Indian population and is meant for practice in India.
  • All postcholecystectomy gallbladder specimens should be opened and examined carefully by the operating surgeon and be sent for histopathological examination.
  • All "incidental" gall bladder cancers (GBCs) picked up on histopathological examination should have an expert opinion.
  • Evaluation of a patient with early GBC should include essential tests: A computed tomography (CT) scan (multi-detector or helical) of the abdomen and pelvis for staging with a CT chest or chest X-ray, and complete blood counts, renal and liver function tests. magnetic resonance imaging/positron emission tomography (PET)-CT are not recommended for all patients.
  • For early stage disease (up to Stage IVA), surgery is recommended. The need for adjuvant treatment would be guided by the histopathological analysis of the resected specimen.
  • Patients with Stage IVB/metastatic disease must be assessed for palliative e.g. endoscopic or radiological intervention, chemotherapy versus best supportive care on an individual basis. These patients do not require extensive workup outside of a clinical trial setting.
  • There is an urgent need for multicenter trials from India covering various aspects of epidemiology (viz., identification of population at high-risk, organized follow-up), clinical management (viz., bile spill during surgery, excision of all port sites, adjuvant/neoadjuvant therapy) and basic research (viz., what causes GBC).

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