Home | About IJMPO | Editorial board | Search | Ahead of print | Current Issue | Archives | Instructions | Subscribe | Advertise | Contact us |  Login 
Indian Journal of Medical and Paediatric Oncology
Search Article 
Advanced search 

 Table of Contents      
Year : 2016  |  Volume : 37  |  Issue : 1  |  Page : 66  

Adenomatoid tumor of cervix: The first case report

1 Department of Pathology, Malda Medical College and Hospital, Malda, West Bengal, India
2 Department of Pathology, Sonoscan Healthcare, Malda, West Bengal, India
3 Department of Pathology, Dishari Healthpoint, Malda, West Bengal, India

Date of Web Publication19-Feb-2016

Correspondence Address:
Krishnendu Mondal
c/o Barendra Nath Mondal, Vill-Fularhat, P.O. and P.S. Sonarpur, South 24 Parganas - 700 150, West Bengal
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0971-5851.177039

Rights and Permissions

How to cite this article:
Banik T, Mondal K, Mandal R. Adenomatoid tumor of cervix: The first case report. Indian J Med Paediatr Oncol 2016;37:66

How to cite this URL:
Banik T, Mondal K, Mandal R. Adenomatoid tumor of cervix: The first case report. Indian J Med Paediatr Oncol [serial online] 2016 [cited 2020 Sep 22];37:66. Available from: http://www.ijmpo.org/text.asp?2016/37/1/66/177039

A 32-year-old female presented with vague lower abdominal pain. Instant per speculum examination and pelvic ultrasound revealed a sessile polypoid mass projecting from the posterior cervical wall. No other clinico-radiologically distinguishable abdominopelvic pathology could be ratified. Polypectomy was performed soon after under regional anesthesia.

Grossly, the mass measured 2.3 cm × 2.2 cm × 2.2 cm. It was covered by glistening pearly white surface epithelium. Cut section exposed a well-defined, whitish, homogeneous mass. Its immaculate delineation from the surface was obvious, even at macroscopic inspection [Figure 1].
Figure 1: Adenomatoid tumor of cervix: Grossly, small globular mass with smooth glistening exterior surface (inset); cut surface is homogeneous, white and well-delineated from surface epithelium

Click here to view

Microscopically, the neoplasm was well-circumscribed and separated from its surface by a rim of fibroconnective tissue. It exhibited an array of architectural patterns: Tubuloglandular structures, microcysts, and solid sheets with focal lymphocytic infiltrates. The flattened-to-cuboidal neoplastic cells featured fine nuclear chromatin, inconspicuous nucleoli, and abundant vacuolated cytoplasm [Figure 2]A-C. Nuclear pleomorphism or mitoses were absent. The overall histomorphology provisionally favored the diagnosis of "adenomatoid tumor" (AT), but differentials such as various endothelial/lipomatous neoplasms needed exclusion. The tumor cells expressed strong immunoreactivity for calretinin [Figure 2]D. Ultimately, it became the maiden case of cervical AT.
Figure 2: Adenomatoid tumor of cervix: Well-circumscribed mass separated from mucosa by a rim of fi broconnective tissue (H and E, ×40) (a). Neoplastic cells in sheets, tubules, microcysts, with focal (arrow) lymphocytic infi ltration (H and E, ×100) (b); contain fi ne nuclear chromatin, inconspicuous nucleoli, and abundant vacuolated cytoplasm (H and E, ×400) (c). Cells positive for calretinin (×400) (d)

Click here to view

Owing to its extreme rarity, AT is a diagnosis of exclusion in the cervix. Comprehensive clinico-radiopathological evaluation aided by mesothelial immunohistochemistry satisfactorily estranges AT from its commoner cervical differentials.

Financial support and sponsorship


Conflicts of interest

There are no conflicts of interest.


  [Figure 1], [Figure 2]


    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

  In this article
   Article Figures

 Article Access Statistics
    PDF Downloaded154    
    Comments [Add]    

Recommend this journal