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Indian Journal of Medical and Paediatric Oncology
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IMAGES IN ONCOLOGY
Year : 2019  |  Volume : 40  |  Issue : 2  |  Page : 282  

A man with headache


1 Department of Medical Oncology, Deenanath Mangeshkar Hospital, Pune, Maharashtra, India
2 Department of Pathology, Deenanath Mangeshkar Hospital, Pune, Maharashtra, India
3 Department of ENT, Deenanath Mangeshkar Hospital, Pune, Maharashtra, India
4 Department of Clinical Hematology, Deenanath Mangeshkar Hospital, Pune, Maharashtra, India

Date of Web Publication17-Oct-2019

Correspondence Address:
Padmaj Kulkarni
Department of Medical Oncology, Deenanath Mangeshkar Hospital, Pune, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijmpo.ijmpo_169_19

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How to cite this article:
Kulkarni P, Mandolkar M, Agarwal R, Bhowmick N, Melinkeri S. A man with headache. Indian J Med Paediatr Oncol 2019;40:282

How to cite this URL:
Kulkarni P, Mandolkar M, Agarwal R, Bhowmick N, Melinkeri S. A man with headache. Indian J Med Paediatr Oncol [serial online] 2019 [cited 2019 Nov 12];40:282. Available from: http://www.ijmpo.org/text.asp?2019/40/2/282/269450

A 49-year-old male presented with intermittent headache and fever. He is a diagnosed case of acute myeloid leukemia posthaploidentical allogenic stem cell transplantation with graft-versus-host disease, cytomegalovirus infection, and pancytopenia secondary to gancyclovir and ruxolitinib. There was tenderness over right maxillary, frontal, and ethmoidal regions. Magnetic resonance imaging showed enhancing soft tissue thickening along medial wall of right orbit with thinning of medial wall of right orbit and right cribriform plate. Black crust was found in nasal cavity and sinuses.

[Figure 1] shows hematoxylin and eosin-stained section of the crust with ×100 magnification.
Figure 1: Histology H and E stain

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  What is the Diagnosis? Top


Answer

For answer to the above question, please refer to page no. 317.

Financial support and sponsorship

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Conflicts of interest

There are no conflicts of interest.

Answer

Mucormycosis.

The section shows necrotic tissue with blood vessel wall showing fungal hyphae. The fragmented hyphae stain positive for periodic acid–Schiff shows irregular walls with right angle branching and aseptation, suggestive of mucormycosis.

Aspergillosis, on the contrary, shows regular walls with acute angle branching.


    Figures

  [Figure 1]



 

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