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Indian Journal of Medical and Paediatric Oncology
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PRACTITIONER SECTION
Year : 2019  |  Volume : 40  |  Issue : 5  |  Page : 176-180

Langerhans cell histiocytosis in a 5-year-old girl: A case report and review of literature


1 Consultant, General Dental Practitioner, Mangala Health Centre, Padil, Mangaluru, Karnataka, India
2 Department of Oral Medicine and Radiology, A B Shetty Memorial Institute of Dental Sciences, Nitte Deemed to be University, Mangaluru, Karnataka, India
3 Department of Oral and Maxillofacial Surgery, A B Shetty Memorial Institute of Dental Sciences, Nitte Deemed to be University, Mangaluru, Karnataka, India
4 Department of Oral Pathology and Microbiology, A B Shetty Memorial Institute of Dental Sciences, Nitte Deemed to be University, Mangaluru, Karnataka, India
5 Research Scholar, Yenepoya Dental College, Yenopoya (Deemed to be) University, Mangaluru, Karnataka, India

Correspondence Address:
Shruthi Rao
2-5-299/4 Sumruddhi, Kuntikana Highway Junction, Bejai Post, Mangaluru - 575 004, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijmpo.ijmpo_258_17

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Langerhans cell histiocytosis (LCH) is an uncommon hematological disorder affecting infants and young children. LCH is a rare disorder of the reticuloendothelial system associated with proliferation of Langerhans cells and mature eosinophils. LCH can involve any bone, but the most common are pelvis, ribs, skull, long bones, vertebra, and facial bones. In the skull, frontal and parietal bones are commonly involved followed by the jaws, where mandible is more commonly affected than the maxilla. In this article, we report a case of LCH in a 5-year-old child involving the mandible. Swelling of one side of the face and aggressive periosteal reaction led to the diagnosis of monostotic LCH. The manuscript also summarizes the results of a literature search in PubMed of reported cases of LCH over the past 10 years.


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