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Indian Journal of Medical and Paediatric Oncology
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PRACTITIONER SECTION
Year : 2020  |  Volume : 41  |  Issue : 3  |  Page : 427-429

Rapidly progressive pleuro-parenchymal fibroelastosis secondary to cyclophosphamide chemotherapy


1 Department of Pulmonary Medicine, Tata Memorial Hospital and Homi Bhabha National Institute, Mumbai, Maharashtra, India
2 Department of Pediatric Oncology, Tata Memorial Hospital and Homi Bhabha National Institute, Mumbai, Maharashtra, India
3 Consultant Radiologist and Partner, Dr. Jankharia's Imaging Centre, Mumbai, Maharashtra, India

Correspondence Address:
Dr. Owais Tisekar
D- 314, Sea Queen Paradise, Sector 10, Kharghar - 410 210, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijmpo.ijmpo_85_19

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Pleuroparenchymal fibroelastosis (PPFE) is a rare progressive interstitial lung disease presenting with predominantly upper-lobe pleural thickening and pulmonary fibrosis. While most cases are idiopathic, it is rarely seen as a complication of infection or following chemotherapy, radiation therapy, and bone marrow transplant. We describe a case of early onset and rapidly progressive PPFE as a complication of cyclophosphamide chemotherapy.


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