Indian Journal of Medical and Paediatric Oncology

CASE REPORT
Year
: 2013  |  Volume : 34  |  Issue : 4  |  Page : 309--312

Primary mediastinal seminoma; resistance and relapse: An aggressive entity


Ankita Nachankar1, Rahul Krishnatry1, Amit Joshi2, Vanita Noronha2, Jai Prakash Agarwal1 
1 Department of Radiation Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India
2 Department of Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India

Correspondence Address:
Jai Prakash Agarwal
Department of Radiation Oncology, Tata Memorial Hospital, Dr. E Borges Road, Parel, Mumbai - 400 012, Maharashtra
India

Seminoma is one of the most radio and chemo sensitive tumors. Aggressive variant of primary mediastinal seminoma (PMS) are rarely described in the literature. We here discuss an interesting case of young male (22 years) presenting with superior vena cava syndrome due to PMS that showed poor response to conventional platinum based chemotherapy and radiotherapy. Furthermore, with a short disease free interval (one year) relapsed at unusual sites of bone and soft-tissue deposits in check. This emphasizes the importance of identifying methods to pre-screen such aggressive variants for more effective treatment options.


How to cite this article:
Nachankar A, Krishnatry R, Joshi A, Noronha V, Agarwal JP. Primary mediastinal seminoma; resistance and relapse: An aggressive entity.Indian J Med Paediatr Oncol 2013;34:309-312


How to cite this URL:
Nachankar A, Krishnatry R, Joshi A, Noronha V, Agarwal JP. Primary mediastinal seminoma; resistance and relapse: An aggressive entity. Indian J Med Paediatr Oncol [serial online] 2013 [cited 2020 Sep 19 ];34:309-312
Available from: http://www.ijmpo.org/article.asp?issn=0971-5851;year=2013;volume=34;issue=4;spage=309;epage=312;aulast=Nachankar;type=0