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  Indian J Med Microbiol
 

Figure 2: Excellent response obtained with 177Lu-DOTATATE peptide receptor radionuclide therapy in a 70-year-old male, diagnosed as primary NET of body and tail of pancreas with multiple hepatic metastasis, MIB-1 index: 12% and no previous surgical intervention. Dual-tracer positron emission tomography-computed tomography 68Ga-DOTATATE positron emission tomography (a) and fluorodeoxyglucose-positron emission tomography (b) demonstrating Krenning Grade IV uptake on baseline 68Ga-DOTATATE positron emission tomography (upper-left image) with relatively low-grade fluorodeoxyglucose (lower-left image). Following three cycles of 177Lu-DOTATATE peptide receptor radionuclide therapy, the metastatic lesion in both scans showed excellent response, whereas the primary tumor showed partial response which was then considered for surgery. (Reproduced with permission from Basu et al.[14])

Figure 2: Excellent response obtained with <sup>177</sup>Lu-DOTATATE peptide receptor radionuclide therapy in a 70-year-old male, diagnosed as primary NET of body and tail of pancreas with multiple hepatic metastasis, MIB-1 index: 12% and no previous surgical intervention. Dual-tracer positron emission tomography-computed tomography <sup>68</sup>Ga-DOTATATE positron emission tomography (a) and fluorodeoxyglucose-positron emission tomography (b) demonstrating Krenning Grade IV uptake on baseline <sup>68</sup>Ga-DOTATATE positron emission tomography (upper-left image) with relatively low-grade fluorodeoxyglucose (lower-left image). Following three cycles of <sup>177</sup>Lu-DOTATATE peptide receptor radionuclide therapy, the metastatic lesion in both scans showed excellent response, whereas the primary tumor showed partial response which was then considered for surgery. (Reproduced with permission from Basu <b>et al</b>.<sup>[14]</sup>)