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Indian Journal of Medical and Paediatric Oncology
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Year : 1995  |  Volume : 16  |  Issue : 1  |  Page : 25-31

Experience with alpha 2-B interferon at medwin cancer centre, hyderabad, india-a preliminary report.


Dept of Oncology, Medwin Cancer Centre, Hyderabad, India

Correspondence Address:
G Sudarshan
Dept of Oncology, Medwin Cancer Centre, Hyderabad, India

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Source of Support: None, Conflict of Interest: None


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Intron-A(Fulford India Ltd.) is an alpha 2-B Interferon and it was introduced into the Indian market 2 years ago. Our aim was to record its usefulness in various malignancies. In total 21 cases received Intron A at our centre during the last 2 years period. This included 6 cases of Chronic Myeloid Leukemia(CML- in chronic phase); 6i cases of Multiple Myeloma Stage III(MM);2 cases of Renal Cell Carcinoma with lung secondaries(RCC); 2 cases of Non-Hodgkins Lymphoma-intermediate grade-Stage II(NHL) 2 cases of Oropharyngeal carcinoma(OC); one case of Myelofibrosis(MF) and 2 cases of Advanced Breast Cancer(ACB). The cases of CML, MM and NHL are still alive and disease free after 2 years of follow up. Both the RCC cases survived more than 1 year. One of the OC cases survived for one year. The MF case died due to pneumonia. The response in breast cancer was poor. Our experience reestablishes the fact that Interon A is useful in CML, MM and NHL. Its use in solid tumors is yet to be established.


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