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Indian Journal of Medical and Paediatric Oncology
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Year : 1995  |  Volume : 16  |  Issue : 1  |  Page : 36-38

Hydroxyurea in early blastic transformation of chronic myeloid leukemia.


Dept of Medicine, King George's Medical College, Lucknow, India

Correspondence Address:
H Agarwal
Dept of Medicine, King George's Medical College, Lucknow, India

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Source of Support: None, Conflict of Interest: None


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We report the role of hydroxyurea in tow patients of chronic myeloid leukemia in early stages of blastic transformation. Both these patients had presented in chronic phase. They attained remission by hydroxyurea and were subsequently maintained in this phase by hydroxyurea 2gm biweekly. On development of bastic transformation hydroxyurea 2gm/day ws instituted along with supportive treatment. No conventional chemotherapy was given. There was significant reduction in number of blast cells, total leucocyte counts, platelets counts with significant symptomatic relief for six to eight months.


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