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Indian Journal of Medical and Paediatric Oncology
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Year : 1995  |  Volume : 16  |  Issue : 2  |  Page : 133-135

Chemotherapy in ovarian cancer experience at railway cancer institute varanasi.


Indian Railway Cancer Institute & Research Centre, Varanasi-221002, India

Correspondence Address:
RC Joshi
Indian Railway Cancer Institute & Research Centre, Varanasi-221002, India

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Source of Support: None, Conflict of Interest: None


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Ovarian cancer is the third most common cancer among women. We have seen 53 patients with ovarian tumour over four years period. Thirty four(63 percent) patients had FIGO stage III and IV disease. Histopathology subtypes were: epithelial cancer in 89 percent and germ cell tumour of ovary in 11 percent of patients. 35 of 53 patients received cisplatin, cyclophosphamide and doxorubicin(CAP, n=12) or cisplatin and cyclophosphamide(CP,n=9)and cisplatin, bleomycin and vinblastine(PVB, n=2). Twenty three patients were evaluable for response. Twenty patients achieved significant response; complete 13(56 percent) and partial response in 7(30 percent) patients. Nausea/vomiting, alopecia were the main side effects due to chemotherapy. Currently, seven patients are alive, disease-free at a median follow up of 2 years(1-3 years). A longer follow up is required to see the impact of chemotherapy on overall and disease-free survival.


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