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Indian Journal of Medical and Paediatric Oncology
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Year : 1995  |  Volume : 16  |  Issue : 2  |  Page : 57-59

Carboplatin for relapsed and resistant acute myeloid leukemia.


Tata Memorial Hospital, Bombay

Correspondence Address:
PSRK Sastry
Tata Memorial Hospital, Bombay

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Source of Support: None, Conflict of Interest: None


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Eight patients of replased or resistant acute myeloid leukemia were treated with carboplatin in the dose of 1500 mg/m2 over five days. One patient had a complete response and two had partial response. The duration of response was 4-8 months. The toxicity associated with the treatment was significant but manageable and there were two early deaths. The overall response rate was 37.5 percent. We conclude that intravenous carboplatin in the dose used needs further evaluation in the treatment of acute myeloid leukemia.


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