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Indian Journal of Medical and Paediatric Oncology
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Year : 1995  |  Volume : 16  |  Issue : 3  |  Page : 168-173

Pemphigus vulgaris and carcinoma of ovary , a case report and review of literature.


Institute Rotary Cancer Institute, New Delhi, India

Correspondence Address:
M Sandhu
Institute Rotary Cancer Institute, New Delhi, India

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Source of Support: None, Conflict of Interest: None


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The association of pemphigus vulgaris and carcinoma of the ovary is extremely rare. A 47 year old lady was diagnosed to have pemphigus; the lesions responded to high dose corticosteroids and cyclophosphamide therapy. Twenty one months later she was detected to have an enlarged right supraclavicular lymph node, right pleural effusion, ascites and an adnexal mass. Investigations-lymph node biopsy, pleural fluid cytology, CA-125 measurements and CAT scan of abdomen and pelvis confirmed the primary ovarian cancer with disseminated disease-FIGO stage IV. She is currently on chemotherapy with cisplatin and cyclophosphamide and has shown significant response. Patients with pemphigus vulgaris when suspected should be investigated to exclude the possibility of a malignant neoplasm as an early diagnosis may improve the prognosis.


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