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Indian Journal of Medical and Paediatric Oncology
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Year : 1995  |  Volume : 16  |  Issue : 4  |  Page : 219-224

Phase II trial of paclitaxel in cases of advanced ovarian carcinoma and other malignancies.


Medical Oncology Department, Tata Memorial Hospital, Bombay, India

Correspondence Address:
BS Parikh
Medical Oncology Department, Tata Memorial Hospital, Bombay, India

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Source of Support: None, Conflict of Interest: None


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Paclitaxel is a new anti-tumour agent. The drug hs been found useful in advanced ovarian malignancies and various other malignancies. Phase II trial of this drug was conducted at Tata Memorial Hospital to study efficacy, safety and toxicity profile of this drug. The response rate was 18 percent for advanced ovarian carcinoma and partial response was seen in one case of choriocarcinoma. Acceptable degree of myelosuppression and alopecia were seen as side effect. No hypersensitivity reactions were noticed. We conclude that Paclitaxel is a reasonably safe drug with good efficacy in various malignancies.


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