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Indian Journal of Medical and Paediatric Oncology
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Year : 1996  |  Volume : 17  |  Issue : 2  |  Page : 111-113

Phenotypic shift of lymphoid blasts at relapse -a case report.


Dept of Medical Oncology, Tata Memorial Hospital, Bombay, India

Correspondence Address:
S Bajpai
Dept of Medical Oncology, Tata Memorial Hospital, Bombay, India

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Source of Support: None, Conflict of Interest: None


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A thirteen year old child with acute lymphoblastic leukemia was found to have only HLA-DR and Immunolglobin heavy chain rearrangement at presentation. After first remission she relapsed with common acute lymphoblastic leukemia antigen positive blasts. Alterations of blast cell phenotype is nwo common in acute lymphoblastic leukemia however, accquiring of the CALL antigen at relapse is rare. The biology of the shifts in phenotype are discussed.


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