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Indian Journal of Medical and Paediatric Oncology
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Year : 1997  |  Volume : 18  |  Issue : 4  |  Page : 132-135

Dexamethasone related perineal paraesthesia : implications and drawbacks.


Department of Medicine, Santokba, Durlabhji Memorial Hospital, Jaipur, India

Correspondence Address:
R Gupta
Department of Medicine, Santokba, Durlabhji Memorial Hospital, Jaipur, India

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Source of Support: None, Conflict of Interest: None


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Dexamethasone phosphate when administered undiluted by intravenous push in dosage reduced even up to 4 mg, produces paraesthesia ranging from mild hot flushes to severe burning and itching, strangely restricted to perineum in 40 to 60 percent of patients. In this study, apart from grading its severity, we have tried to emphasize its greater recognition among those engaged in its administration. In addition to recommend that always mention a note of it on patient's file, we propose a cheaper and easy approach for its use in different required dosages in a suitable dilutional form. This concept should help build a better compliance with the cancer chemotherapy and should improve comprehensive cancer care.


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