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Indian Journal of Medical and Paediatric Oncology
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Year : 1998  |  Volume : 19  |  Issue : 1  |  Page : 19-22

Profile of hepatitis in cancer patients.

Department of Medical Oncology, Shere-i-Kashmir Institute of Medical Sciences, Srinagar

Correspondence Address:
SA Aziz
Department of Medical Oncology, Shere-i-Kashmir Institute of Medical Sciences, Srinagar

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During the period of July 1993 till March 1995, 409 new admissions were made in the Department of Medical Oncology, SKIMS (230 males, 179 females). Of these 23 patients were diagnosed to have hepatocellular jaundice of infectious aetiology (13 males and 10 females). Hepatitis B was seen in 9 patients (2.20 per cent), Hepatitis C in 5 patients (1.22 percent), Hepatitis E in 4 patients (0.97 per cent), the nature of infection could not be ascertained. Protracted clinical course including short incubation period, prolonged icteric stage and convalescence were observed, Indices of liver cell damage were elevated much more than the patients of uncomplicated hepatitis. Histopathological features were identical to those seen in uncomplicated hepatitis. There were 9 deaths (39.1 per cent) attributable to hepatocellular failure in these patients. Female sex, higher values of bilirubin and liver enzymes, low serum albumin and deranged coagulation indices were identified as bad prognostic factors.

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