Home | About IJMPO | Editorial board | Search | Ahead of print | Current Issue | Archives | Instructions | Subscribe | Advertise | Contact us |  Login 
Indian Journal of Medical and Paediatric Oncology
Search Article 
  
Advanced search 
 
Year : 1998  |  Volume : 19  |  Issue : 1  |  Page : 3-8

Recombinant human erythropoietin therapy for cisplatin associated anaemia : a pilot study.


Department of Medical Oncology & Haematology, Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi

Correspondence Address:
L Kumar
Department of Medical Oncology & Haematology, Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi

Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Sixteen patients with cisplatin associated anaemia (haemoglobin less than 9 gm per cent) received recombinant human erythropoietin (EPO), 50 U/kg subcutaneously three times a week for three weeks on an out patient basis. Seven of fifteen patients responded (increase in haemoglobin to greater than 10 g per cent); six following an well; headache, fatigue, nausea and feverish feeling being the main side effects. No episodes of hypertension or thrombo-haemorrhagic complications were detected. We conclude that recombinant human erythropoietin is safe and well tolerated in the recombinant human erythropoietin is safe and well tolerated in the treatment of cisplatin induced anaemia. It results in response rate of about 50 per cent following low dose treatment (50 U/kg three times a week). Further studies are needed to determine the optimum dose. schedule of EPO therapy and its impact on transfusion requirements.


[PDF Not available]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed680    
    Printed46    
    Emailed0    
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal