Home | About IJMPO | Editorial board | Search | Ahead of print | Current Issue | Archives | Instructions | Subscribe | Advertise | Contact us |  Login 
Indian Journal of Medical and Paediatric Oncology
Search Article 
  
Advanced search 
 
Year : 2005  |  Volume : 26  |  Issue : 4  |  Page : 25-30

Carcinoma gallbladder : Clinical features and workup


Department of Gastroenterology and Human Nutrition All India Institute of Medical Sciences, Ansari Nagar, New Delhi-110029, India

Correspondence Address:
M Sharma
Department of Gastroenterology and Human Nutrition All India Institute of Medical Sciences, Ansari Nagar, New Delhi-110029, India

Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Carcinoma of the gallbladder has aggressive tumour biology. The disease is confined to gallbladder wall at the time presentation in only about 15-20 percent patients and 80 percent have locoregional and/or distant spread making them unresectable at the time of diagnosis. Absence of specific signs or symptoms makes the diagnosis of carcinoma GB difficult at an early stage. Presence of jaundice is a poor prognostic indicator and the cancer is unresectable in about half of patients by the time jaundice appears. There are five types of presentation of carcinoma GB: presentation with features of acute cholecystitis, presentation with chronic cholecystitis, presentation with chronic cholecystitis, presentation with biliary tract symptoms (jaundice, abdominal pain), presentation like malignant tumours outside the biliary tree (invasion of surrounding structures) and benign manifestations outside the biliary tract such as gastrointestinal bleeding. Trans-abdominal ultrasound (US) is a sensitive technique to detect carcinoma GB and US guided fine needle aspiration is almost diagnostic (sensitivity 88 percent and specificity 100 percent). Computed tomography is required to assess resectability and spread of disease. The natural history of disease is quite dismal and survival rates are less than a year once survival lies in early diagnosis of carcinoma of the gallbladder.


[PDF Not available]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed794    
    Printed54    
    Emailed1    
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal