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Indian Journal of Medical and Paediatric Oncology
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Year : 2005  |  Volume : 26  |  Issue : 4  |  Page : 31-35

Profile of gall bladder cancer cases in Bihar

Regional Cancer Centre, Indira Gandhi Institute of Medical Sciences, Sheikhpura Patna-8000013

Correspondence Address:
RR Prasad
Regional Cancer Centre, Indira Gandhi Institute of Medical Sciences, Sheikhpura Patna-8000013

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Source of Support: None, Conflict of Interest: None

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Gallbladder cancer cases are commonly seen in state of Bihar in three major cancer centers (treating more than 2000 cancer cases per year each); Patna Medical College (P.M.C.H), Mahavir Cancer Sansthan (MCS), and Regional Cancer Center (RCC). Based on limited hospital-based data from these three cancer centers, a retrospective analysis of cases of cancer of gallbladder was performed to look into patterns of care of such patients. A total of 1203 cases were seen between periods of 1st July 2005 to 30th June 2006. In PMCH, MCS, RCC 141,594,468 cases of cancer of gallbladder were seen, respectively during this period. Most cases presented in advance stages leading to poor outcome. The age range varied from 16 years to 100 years of age, with mean age of 48 years in females and 55 years in male. Jaundice at presentation was in 38.66 percent cases. Adenocarcinoma was the most common variety seen in 99 percent cases. Radical surgery was performed in minority of cases while use of postoperative radiotherapy was infrequent. Various combination regimens of chemotherapeutic drugs used included Cisplatin, 5 Fluorouracil (5-FU), Oxaliplatinum, Gemicitabine, Irinotecan, and Capecitabine etc. However, many patients did not complete proposed chemotherapy cycles on account of progressive disease, toxicities of chemotherapeutic agents and due to logistic reasons. Use of tumour marker was limited to one center and included Ca19-9 and CEA. There are limited research and clinical trial works related to gallbladder, undergoing in these centers.

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