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1Multi-targeted kinase inhibition alleviates mTOR inhibitor resistance in triple-negative breast cancer
Jichao He,Ronan P. McLaughlin,Vera van der Noord,John A. Foekens,John W. M. Martens,Gerard van Westen,Yinghui Zhang,Bob van de Water
Breast Cancer Research and Treatment.2019;178(2)263
2Potentiating apoptosis and modulation of p53, Bcl2, and Bax by a novel chrysin ruthenium complex for effective chemotherapeutic efficacy against breast cancer
Souvik Roy,Anweshan Sil,Tania Chakraborty
Journal of Cellular Physiology.2019;234(4)4888
3Dual inhibition of mTORC1 and mTORC2 perturbs cytoskeletal organization and impairs endothelial cell elongation
Kiyomi Tsuji-Tamura,Minetaro Ogawa
Biochemical and Biophysical Research Communications.2018;497(1)326
4Effect of visceral metastases on the efficacy and safety of everolimus in postmenopausal women with advanced breast cancer: Subgroup analysis from the BOLERO-2 study
Mario Campone,Thomas Bachelot,Michael Gnant,Ines Deleu,Hope S. Rugo,Barbara Pistilli,Shinzaburo Noguchi,Mikhail Shtivelband,Kathleen I. Pritchard,Louise Provencher,Howard A. Burris,Lowell Hart,Bohuslav Melichar,Gabriel N. Hortobagyi,Francis Arena,José Baselga,Ashok Panneerselvam,Aurelia Héniquez,Mona El-Hashimyt,Tetiana Taran,Tarek Sahmoud,Martine Piccart
European Journal of Cancer.2013;49(12)2621
5Geranylgeranyltransferase I regulates HIF-1a promoting glioblastoma cell migration and invasion
Xiuping Zhou,Zhi Liu,Qiong Shi,Jiantong Jiao,Wenbin Bian,Xu Song,Jianbing Mo,Ben sang,Yinfu Xu,Jinming Qian,Yuewen Chao,Rutong Yu
Journal of Neuro-Oncology.2013;112(3)365
6The Fate of the Tumor in the Hands of Microenvironment: Role of TAMs and mTOR Pathway
Danilo Figueiredo Soave,Marina Pacheco Miguel,Fernanda Dias Tomé,Liliana Borges de Menezes,Patrícia Resende Alo Nagib,Mara Rúbia Nunes Celes
Mediators of Inflammation.2016;2016(3)1
7Curcumin analogue 1,5-bis(4-hydroxy-3-((4-methylpiperazin-1-yl)methyl)phenyl)penta-1,4-dien-3-one mediates growth arrest and apoptosis by targeting the PI3K/AKT/mTOR and PKC-theta signaling pathways in human breast carcinoma cells
Gamal Badr,Halise Inci Gul,Cem Yamali,Amal A.M. Mohamed,Badr M. Badr,Mustafa Gul,Ahmad Abo Markeb,Nagwa Abo El-Maali
Bioorganic Chemistry.2018;78(3)46
818F-FDG PET in Patients with Primary Systemic Anaplastic Large Cell Lymphoma: Differential Features According to Expression of Anaplastic Lymphoma Kinase
Dong Yun Lee,Jong Jin Lee,Jin Yong Kim,Seol Hoon Park,Sun-Young Chae,Shin Kim,Dok Hyun Yoon,Cheolwon Suh,Jooryung Huh,Jin-Sook Ryu
Nuclear Medicine and Molecular Imaging.2013;47(4)249
9Gossypol sensitizes the antitumor activity of 5-FU through down-regulation of thymidylate synthase in human colon carcinoma cells
Dan Yang,Jinglei Qu,Xiujuan Qu,Yubo Cao,Ling Xu,Kezuo Hou,Wanyu Feng,Yunpeng Liu
Cancer Chemotherapy and Pharmacology.2015;76(3)575
10Alzheimer’s Disease and Cancer: When Two Monsters Cannot Be Together
Shohreh Majd,John Power,Zohreh Majd
Frontiers in Neuroscience.2019;13(3)575
11Vanadium quercetin complex attenuates mammary cancer by regulating the P53, Akt/mTOR pathway and downregulates cellular proliferation correlated with increased apoptotic events
Souvik Roy,Sritama Banerjee,Tania Chakraborty
12Potential impact of mTOR inhibitors on cervical squamous cell carcinoma: A systematic review
Daniele Xavier Assad,Silvia Taveira Elias,Andréia Cristina Melo,Carlos Gil Ferreira,Graziela De Luca Canto,Eliete Neves Silva Guerra
Oncology Letters.2016;12(5)4107
13A Review of mTOR Pathway Inhibitors in Gynecologic Cancer
Andréia Cristina de Melo,Eduardo Paulino,Álvaro Henrique Ingles Garces
Oxidative Medicine and Cellular Longevity.2017;2017(5)1
14Grape seed extract and resveratrol prevent 4-nitroquinoline 1-oxide induced oral tumorigenesis in mice by modulating AMPK activation and associated biological responses
Sangeeta Shrotriya,Alpna Tyagi,Gagan Deep,David J. Orlicky,Joshua Wisell,Xiao-Jing Wang,Robert A. Sclafani,Rajesh Agarwal,Chapla Agarwal
Molecular Carcinogenesis.2015;54(4)291
15Nuclear Magnetic Resonance-Based Metabolomics Approach to Evaluate the Prevention Effect of Camellia nitidissima Chi on Colitis-Associated Carcinogenesis
Ming-Hui Li,Hong-Zhi Du,Gui-Ju Kong,Li-Bao Liu,Xin-Xin Li,Sen-Sen Lin,Ai-Qun Jia,Sheng-Tao Yuan,Li Sun,Jun-Song Wang
Frontiers in Pharmacology.2017;8(4)291
16Circular RNA alterations are involved in resistance to avian leukosis virus subgroup-J-induced tumor formation in chickens
Xinheng Zhang,Yiming Yan,Xiaoya Lei,Aijun Li,Huanmin Zhang,Zhenkai Dai,Xinjian Li,Weiguo Chen,Wencheng Lin,Feng Chen,Jingyun Ma,Qingmei Xie
17UBE2C Drives Human Cervical Cancer Progression and Is Positively Modulated by mTOR
An-Jen Chiang,Chia-Jung Li,Kuan-Hao Tsui,Chung Chang,Yuan-chin Ivan Chang,Li-Wen Chen,Tsung-Hsien Chang,Jim Jinn-Chyuan Sheu
18Effects of bisphosphonates on human esophageal squamous cell carcinoma cell survival
T. Minegaki,S. Fukushima,C. Morioka,H. Takanashi,J. Uno,S. Tsuji,S. Yamamoto,A. Watanabe,M. Tsujimoto,K. Nishiguchi
Diseases of the Esophagus.2016;29(6)656
19Homeodomain-containing protein HOXB9 regulates expression of growth and angiogenic factors, facilitates tumor growth in vitro and is overexpressed in breast cancer tissue
Bishakha Shrestha,Khairul I. Ansari,Arunoday Bhan,Sahba Kasiri,Imran Hussain,Subhrangsu S. Mandal
The FEBS Journal.2012;279(19)3715
20Everolimus in combination with letrozole inhibit human breast cancer MCF-7/Aro stem cells via PI3K/mTOR pathway: an experimental study
Yan Liu,Xiaobei Zhang,Jingjing Liu,Guofang Hou,Sheng Zhang,Jin Zhang
Tumor Biology.2014;35(2)1275
21Reversal effects of pantoprazole on multidrug resistance in human gastric adenocarcinoma cells by down-regulating the V-ATPases/mTOR/HIF-1a/P-gp and MRP1 signaling pathway in vitro and in vivo
Min Chen,Shu-Ling Huang,Xiao-Qi Zhang,Bin Zhang,Hao Zhu,Vincent W. Yang,Xiao-Ping Zou
Journal of Cellular Biochemistry.2012;113(7)2474
22Everolimus-induced nephrotic syndrome precipitated by interaction with voriconazole in a patient with Hodgkin's lymphoma
P. N. Tran,L. C. Pinter-Brown
Journal of Clinical Pharmacy and Therapeutics.2017;42(6)776
23Vascular endothelial growth factor: An important molecular target of curcumin
Maryam Saberi-Karimian,Niki Katsiki,Michele Caraglia,Mariarosaria Boccellino,Muhammed Majeed,Amirhossein Sahebkar
Critical Reviews in Food Science and Nutrition.2019;59(2)299
24Hypoxia and metabolic adaptation of cancer cells
K L Eales,K E R Hollinshead,D A Tennant
25Systemic and Nonrenal Adverse Effects Occurring in Renal Transplant Patients Treated with mTOR Inhibitors
Gianluigi Zaza,Paola Tomei,Paolo Ria,Simona Granata,Luigino Boschiero,Antonio Lupo
Clinical and Developmental Immunology.2013;2013(1)1
26Everolimus with paclitaxel and carboplatin as first-line treatment for metastatic large-cell neuroendocrine lung carcinoma: a multicenter phase II trial
P. Christopoulos,W. Engel-Riedel,C. Grohé,C. Kropf-Sanchen,J. von Pawel,S. Gütz,J. Kollmeier,W. Eberhardt,D. Ukena,V. Baum,I. Nimmrich,C. Sieder,P.A. Schnabel,M. Serke,M. Thomas
Annals of Oncology.2017;28(8)1898
27A Case of Everolimus-induced Interstitial Pneumonia with Infiltrated Opacities in the Lung Field: Case Report
Daisuke Koyama,Fumio Kumasawa,Naotaka Akutsu,Mikio Shiba,Kyoko Akiyama,Tsukasa Hataoka,Yoshitaka Shintani,Yoshihiro Sato,Tetsuo Shimizu,Shinichi Hayashi,Tomoko Kobayashi,Katsuhiko Sato,Kenya Yamaguchi,Yasuhiro Gon,Noriaki Takahashi,Satoru Takahashi,Shu Hashimoto
Journal of Nihon University Medical Association.2013;72(3)159
28Decrypting the Molecular Mechanistic Pathways Delineating the Chemotherapeutic Potential of Ruthenium-Phloretin Complex in Colon Carcinoma Correlated with the Oxidative Status and Increased Apoptotic Events
Guoguo Jin,Zhenjiang Zhao,Tania Chakraborty,Aikyadeep Mandal,Arka Roy,Souvik Roy,Zhiping Guo
Oxidative Medicine and Cellular Longevity.2020;2020(3)1
29Antitumor effect of the mTOR inhibitor everolimus in combination with trastuzumab on human breast cancer stem cells in vitro and in vivo
Yuanxi Zhu,Xiaobei Zhang,Yan Liu,Sheng Zhang,Jingjing Liu,Yi Ma,Jin Zhang
Tumor Biology.2012;33(5)1349
30Optimal use of recombinant granulocyte colony-stimulating factor with chemotherapy for solid tumors
Marco Danova,Sandro Barni,Lucia Del Mastro,Romano Danesi,Giovanni L Pappagallo
Expert Review of Anticancer Therapy.2011;11(8)1303
31Deciphering the biochemical and molecular mechanism underlying the in vitro and in vivo chemotherapeutic efficacy of ruthenium quercetin complex in colon cancer
Souvik Roy,Rituparna Das,Balaram Ghosh,Tania Chakraborty
Molecular Carcinogenesis.2018;57(6)700
32Role of mTOR Inhibitors in Growth Hormone-Producing Pituitary Adenomas Harboring Different FGFR4 Genotypes
Shahrzad Jalali,Eric Monsalves,Toru Tateno,Gelareh Zadeh
33IGF2 and IGF1R in pediatric adrenocortical tumors: roles in metastasis and steroidogenesis
Régia Caroline Peixoto Lira,Paola Fernanda Fedatto,David Santos Marco Antonio,Letícia Ferro Leal,Carlos Eduardo Martinelli,Margaret de Castro,Silvio Tucci,Luciano Neder,Leandra Ramalho,Ana Luiza Seidinger,Izilda Cardinalli,Maria José Mastellaro,José Andres Yunes,Silvia Regina Brandalise,Luiz Gonzaga Tone,Sonir Roberto Rauber Antonini,Carlos Alberto Scrideli
Endocrine-Related Cancer.2016;23(6)481
34Targeting amino acid metabolism in cancer growth and anti-tumor immune response
Elitsa Ananieva
World Journal of Biological Chemistry.2015;6(4)281
35A serum metabolomic fingerprint of bevacizumab and temsirolimus combination as first-line treatment of metastatic renal cell carcinoma
Elodie Jobard,Ellen Blanc,Sylvie Négrier,Bernard Escudier,Gwenaelle Gravis,Christine Chevreau,Bénédicte Elena-Herrmann,Olivier Trédan
British Journal of Cancer.2015;113(8)1148
36The Mammalian Target of Rapamycin–70-kDa Ribosomal Protein S6 Kinase Axis Inhibits the Biological Function of Tongue Squamous Cell Carcinoma
Chen Yi,Zixian Huang,Zhiquan Huang,Xiaopeng Zhao,Haigang Li,Jianguang Wang
Journal of Oral and Maxillofacial Surgery.2019;77(9)1928
37Clinical and Pre-Clinical Evidence of Carbonic Anhydrase IX in Pancreatic Cancer and Its High Expression in Pre-Cancerous Lesions
Sabina Strapcova,Martina Takacova,Lucia Csaderova,Paola Martinelli,Lubomira Lukacikova,Viliam Gal,Juraj Kopacek,Eliska Svastova
38Clinical and Pre-Clinical Evidence of Carbonic Anhydrase IX in Pancreatic Cancer and Its High Expression in Pre-Cancerous Lesions
Anna R. Cooper,Wakenda Tyler,Emily E. Carmody
39Garcinol acts as an antineoplastic agent in human gastric cancer by inhibiting the PI3K/AKT signaling pathway
Yuanyuan Zheng,Chuanyong Guo,Xiaoping Zhang,Xiaoli Wang,A'?uo Ma
Oncology Letters.2020;20(1)667
40Empagliflozin and Doxorubicin Synergistically Inhibit the Survival of Triple-Negative Breast Cancer Cells via Interfering with the mTOR Pathway and Inhibition of Calmodulin: In Vitro and Molecular Docking Studies
Shenouda G. Eliaa,Ahmed A. Al-Karmalawy,Rasha M. Saleh,Mohamed F. Elshal
ACS Pharmacology & Translational Science.2020;3(6)1330
41Mesenchymal stem cell-based HSP70 promoter-driven VEGFA induction by resveratrol promotes angiogenesis in a mouse model
Young-Bin Chen,Ying-Wei Lan,Tsai-Hsien Hung,Lih-Geeng Chen,Kong-Bung Choo,Winston TK Cheng,Hsuan-Shu Lee,Kowit-Yu Chong
Cell Stress and Chaperones.2015;20(4)643
42AZD2014 Radiosensitizes Oral Squamous Cell Carcinoma by Inhibiting AKT/mTOR Axis and Inducing G1/G2/M Cell Cycle Arrest
Chih-Chia Yu,Hsien-bin Huang,Shih-Kai Hung,Hui-Fen Liao,Ching-Chih Lee,Hon-Yi Lin,Szu-Chin Li,Hsu-Chueh Ho,Chung-Lin Hung,Yu-Chieh Su,Chih-Pin Chuu
PLOS ONE.2016;11(3)e0151942
43Role of mTOR Signaling in Tumor Microenvironment: An Overview
Fabiana Conciatori,Chiara Bazzichetto,Italia Falcone,Sara Pilotto,Emilio Bria,Francesco Cognetti,Michele Milella,Ludovica Ciuffreda
International Journal of Molecular Sciences.2018;19(8)2453