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Indian Journal of Medical and Paediatric Oncology
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COURTING CONTROVERSY

Can cancer survivors donate convalescent plasma for the treatment of COVID-19?


 National Oncology Centre, The Royal Hospital, Muscat, Sultanate of Oman

Correspondence Address:
Ajit Venniyoor,
National Oncology Centre, The Royal Hospital, Post Box 1331, Seeb, Postal Code 111, Muscat
Sultanate of Oman
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijmpo.ijmpo_377_20

Convalescent plasma (CP) obtained from patients who have recovered from coronavirus disease 2019 (COVID-19) infection contains neutralizing antibodies against the severe acute respiratory syndrome-coronavirus-2 virus and is being used in critically ill patients to boost their immunity. Cancer survivors who are affected by COVID-19 are potential donors of CP. However, twin questions often asked are, firstly, what is the risk of transmitting cancer through blood and blood products donated by a cancer survivor, and secondly, will the CP donated by a cancer survivor have enough antibody titers to have a clinically significant effect? The evidence regarding the safety and efficacy of CP donated by a cancer survivor is examined in this article, and the conclusions are positive. However, regulatory changes will be needed specific to Indian guidelines.


    

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