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Indian Journal of Medical and Paediatric Oncology
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   1998| September  | Volume 19 | Issue 3  
    Online since May 30, 2009

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Breast Cancer followed by cervix cancer : a rare form of double malignancy
D Mohanti, YH Poharel, S Kumar, BM Biswal, L Kumar
September 1998, 19(3):90-93
Breast cancer patients are prone to develop a second primary malignant tumor; common sites being opposite breast, endometrium and ovary. Second primary cancer of cervis is rare. Two patients (age 36, and 48 years) with breast cancer developed primary cervical cancer, 2 and 9 years later. First patient with FIGO, stage IB underwent Wertheim's radical hysterectomy followed by adjuvant chemotherapy and is currently on radiotherapy. Second patient with FIGO, stage IIB achieved complete response with pelvic radiotherapy and is currently alive and disease-free 5 years since the diagnosis. Breast cancer patients must be kept on a close and longterm follow up.
[ABSTRACT]   Full text not available   
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Primary rhabdomyosarcoma of the breast, case report and review of literature
N Geetha, P Kusumkumary, E Abraham, S Vijayamohan, K Nair
September 1998, 19(3):97-100
Malignant neoplasms of the breast are rare in children and represent less than 1 percent of all neoplasms in those under 20 years of age. The occurance of rhabdomysarcoma as a primary tumor in the breast is uncommon. We describe a twelve year old girl who presented with primary embryonal rhabdomyosarcoma of the breast. She underwent conservative surgery, received combination chemotherapy and radiotherapy. The child is alive and disease free at 45 months with good cosmesis of the breast. The literature on primary rhabdomyosarcoma of the breast is reviewed.
[ABSTRACT]   Full text not available   
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Combination of netilmicine (once daily or thrice daily) with either ceftriaxone ar ampicillin cloxacilin as emperical therapy for febrile neutropenic patients
SV Nath, PM Shah, AS Anand, BJ Parikh, KM Patel, SN Shukla, SS Talati, SA Shah, P Goswami, N Shah, RP Shah, KP Sajanani, Parekh/BB, JN Bhatia
September 1998, 19(3):83-89
Febrile neutropenia is a frequent complication in patients undergoing treatment for neoplastic disease. The optimum emperic antibiotic regimen consists of an aminoglycoside and B-lactum antibiotic. The safety and efficacy of once a day dose of netilmicin has been investigated in febrile neutropenic patients in this study. Thirty six patients were randomised into three groups. Group I consisted of Netilmycin and Ceftriaxone administration in single daily dose. In group II, Netilmycin was administered three times a day with single dosing of Ceftriaxone while in Group III single dosing of Netilmycin was combined with Ampicillin and Cloxacillin. The mean duration of neutropenia was similar in the three groups. The commonest site of infection was the respiratory tract. Once a day administration of antibiotics was more convenient as in group I and two patients could take treatment on an outpatient basis. Once a day administration of Ceftriaxone and Netilmycin is as effective as three times daily dosing of netilmicin with once daily ceftriaxone and can be considered as an emperical line of treatment for patients with febrile neutropenia.
[ABSTRACT]   Full text not available   
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Acute leukemia following treatment of hodgkins disease
SA Aziz, M Ahmed, G Mohd
September 1998, 19(3):94-96
A 12 years old boy, diagnosed as Hodgkin's disease-Lymphocyte-depletion, stage IV B, in 1990, developed pancytopenia almost 4.5 years later, this very soon evolved into Acute Non lymphoblastic leukemia(M2).
[ABSTRACT]   Full text not available   
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Strategies of reduce the mortality from childhood Cancer in developing countries
N Lalitha, L Appaji, BS Arunakumari
September 1998, 19(3):76-82
Taking guidelines from the west in reducing mortality from paediatric cancer, strategies that can be adopted in developing countries are, to understand magnitude of problem, to know the incidence and pattern and strategies for early diagnosis, for optimal treatment including and pattern and strategies for early diagnosis, for optimal treatment including supportive care, and to prevent late complications. Preliminary experiences from KIMIO, Bangalore, in this direction are highlighted. Children under 15 years from more than 1/3rd of the population. The average cancer incidence in children under 15 years is 5 percent in boys and 2.5 percent in girls. Lymphoid neoplasias (A.L.L and NHL) is the most common cancer, 35-40 percent in boys and 25-30 percent in girls. Next comes Hodgkin's disease and brain tumours in boys and brain tumours in girls. Improved trends in survival with reference to Hodgkin's disease and A.L.L are given as examples. 25 percent of total Hodgkin's diseases are under 15 years of age and majority present with 'B' symptoms and Ann Arbor Stages III and IV. Before 1981, with only RT none survived beyond 1 year with CT (COPP) and involved field radiotherapy to bulky sites, present 5 years survival has reached more than 85 percent. Majority of A.L.L belong to high risk group and with introduction of protocol based treatment since 1987 (MCP 841 of NCI, USA), 30 months survival is at present more than 60 percent.
[ABSTRACT]   Full text not available   
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Second malignant neoplasms after childhood
AS Anand
September 1998, 19(3):73-75
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