Serum lipid and oral cancer
CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2011; 32(03): 184
DOI: DOI: 10.4103/0971-5851.92833
Article published online:
06 August 2021
© 2011. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)
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The recent report on serum lipid and oral cancer is very interesting. Chawa et al. concluded that “An inverse relationship was found between the lipid levels and the occurrence of oral cancer.” As Chawda et al. noted, the main problem of this work is the limitation in the number of subjects. However, there are also other additional concerns. The quality control of the blood lipid analysis in this report has to be mentioned. “Analysis on the same day” might be problematic if it is delayed for many hours. Nevertheless, the mentioned method for analysis seems very strange. “CHOD-PAP” is not the technique that can be used for analysis of all parameters. The triglyceride has to be measured by the glycerol-3-phosphate oxidase - phenol - aminophenazone (GPO-PAP) technique. Also, the analyzer, Erba chem, seems to be not feasible for analysis for very low density lipoprotein (VLDL). With many questions on the methodology, the value of the conclusion seems to be very limited.'